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Where the Boys Arent : Dioxin and the Sex Ratio

By Jongbloet, Piet Hein

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Book Id: WPLBN0000096115
Format Type: PDF eBook
File Size: 0.5 MB
Reproduction Date: 2005

Title: Where the Boys Arent : Dioxin and the Sex Ratio  
Author: Jongbloet, Piet Hein
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Jongbloet, P. H. (n.d.). Where the Boys Arent : Dioxin and the Sex Ratio. Retrieved from

Government Reference Publication

Excerpt: Mocarelli and colleagues (1,2) compared about 750 people in a cohort from the most contaminated area to 40,000 people from two zones that were less contaminated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or dioxin) after the explosion at a herbicide plant in Seveso, Italy. The authors found a lower proportion of male offspring from exposed fathers (77:100) and a tendency to more male offspring (120:100) from exposed mothers. Clapp and Ozonoff (3) describe these results as ?intriguing, worrying and provocative? (p. 848). A similar decrease of male offspring was found in an Austrian chloracne cohort, in which only fathers were exposed to dioxin (4). In the human ejaculate, the proportion of X- and Y-bearing sperm is always equal (5,6), and deviation of this equality has never been identified in animals or humans, regardless of whether the sperm is normal or manipulated (7). However, the normal male-to-female ratio at conception, or primary sex ratio (PSR), is not 100 boys for 100 girls, but is presumed to be much higher, while the secondary sex ratio (SSR) at birth is about 105?106:100 (5).


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